Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.41 |
| ▸ | TACR3 | P29371 | 4/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785680 | 0.83 | NPC1 (0.41) | KMT2ASLC6A9SLC6A5ALDH1A1EGFR | |
| SCHEMBL27553469 | 0.79 | AKR1C3 (0.43) | MEN1KMT2ASLC6A9ALDH1A1SLC6A2 | |
| SCHEMBL7787470 | 0.79 | AKR1C3 (0.43) | MEN1KMT2ASLC6A9ALDH1A1SLC6A2 | |
| SCHEMBL28073510 | 0.77 | MTOR (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7780329 | 0.77 | ALDH1A1 (0.39) | KMT2ASLC6A9SLC6A5ALDH1A1 | |
| SCHEMBL7787615 | 0.77 | MAPKAPK2 (0.33) | SLC6A9SLC6A5SLC6A2SLC6A4 | |
| SCHEMBL7787788 | 0.77 | CASR (0.37) | SLC6A9SLC6A5ALDH1A1KCNK3SLC6A2 | |
| SCHEMBL28277977 | 0.75 | LOXL2 (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7780766 | 0.75 | IDO1 (0.39) | ALDH1A1SLC6A2SLC6A4CPN1CPB2 | |
| SCHEMBL7780426 | 0.75 | SLC6A2 (0.41) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |