Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 3/20 | 0.46 |
| ▸ | CTSA | P10619 | 5/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194899 | 0.92 | ITGB3 (0.44) | CTSAITGB3ITGA2BF10 | |
| SCHEMBL7790178 | 0.91 | CTSA (0.41) | EEF2KCTSAITGB3ITGA2BF10 | |
| SCHEMBL7781206 | 0.90 | ITGB3 (0.42) | CTSAITGB3ITGA2BF10 | |
| SCHEMBL7788355 | 0.90 | MMP12 (0.47) | KCNQ3KCNQ2ITGB3ITGA2BWDR5 | |
| SCHEMBL7789969 | 0.90 | CYP26A1 (0.42) | CTSAITGB3ITGA2BF10 | |
| SCHEMBL7785658 | 0.87 | LMNA (0.44) | CTSAITGB3ITGA2BF10 | |
| SCHEMBL7788749 | 0.87 | ITGB3 (0.44) | CTSAITGB3ITGA2B | |
| SCHEMBL7786214 | 0.86 | S1PR3 (0.41) | CTSAITGB3ITGA2B | |
| SCHEMBL7786241 | 0.85 | CTSA (0.46) | CTSAITGB3ITGA2B | |
| SCHEMBL7790073 | 0.85 | CYP26A1 (0.46) | CTSAITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |