Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519193 | 0.67 | SMN1; SMN2 (0.54) | HPGDKDM4EALDH1A1MAPK1RAB9A | |
| SCHEMBL1226530 | 0.67 | SMN1; SMN2 (0.54) | HPGDKDM4EALDH1A1MAPK1RAB9A | |
| SCHEMBL29508765 | 0.62 | FBP1 (0.48) | — | |
| SCHEMBL3290451 | 0.59 | SLC5A2 (0.53) | SLC5A2RAB9ANPC1 | |
| SCHEMBL25084179 | 0.59 | RAB9A (0.51) | MAPK1RAB9AMAPTNPC1POLB | |
| SCHEMBL7901236 | 0.58 | ITPR3 (0.32) | — | |
| SCHEMBL10828925 | 0.57 | RAB9A (0.45) | HPGDALDH1A1MAPK1RAB9AMAPT | |
| SCHEMBL665339 | 0.57 | RAB9A (0.75) | HPGDKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL612151 | 0.57 | NPC1 (0.61) | HPGDKDM4EALDH1A1HSD17B10MAPK1 | |
| Methacrylic Acid SCHEMBL21905373 | 0.56 | ALDH1A1 (0.48) | HPGDKDM4EALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822192-B1 | Inhibitors of beta-glucuronidase | HOECHST AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0822192-A2 | Inhibitors of beta-glucuronidase | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-04 | — | — | EP | disclosed |