Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782299 | 0.88 | PDE7A (0.45) | LMNAMEN1KMT2AL3MBTL1ADORA3 | |
| SCHEMBL23119669 | 0.77 | LMNA (0.67) | LMNAHTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8888752 | 0.77 | TSHR (0.40) | LMNAHTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7782330 | 0.73 | PSMB8 (0.47) | LMNAHTTMEN1KMT2AADORA3 | |
| SCHEMBL6977596 | 0.69 | KDM4E (0.73) | LMNAHTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3150851 | 0.67 | PDE7A (0.51) | LMNAMEN1KMT2AL3MBTL1ADORA3 | |
| SCHEMBL30910102 | 0.67 | PDE7A (0.51) | LMNAMEN1KMT2AL3MBTL1ADORA3 | |
| SCHEMBL5667519 | 0.67 | TSHR (0.42) | LMNAMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL5361973 | 0.67 | TSHR (0.42) | LMNAMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL6283505 | 0.67 | PDE7A (0.77) | HTTMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809635-B1 | ALPHA-SUBSTITUTED HYDRAZIDES HAVING CALPAIN INHIBITORY ACTIVITY | WARNER LAMBERT CO (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0809635-A1 | ALPHA-SUBSTITUTED HYDRAZIDES HAVING CALPAIN INHIBITORY ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1996025403-A1 | α-SUBSTITUTED HYDRAZIDES HAVING CALPAIN INHIBITORY ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1996-08-22 | — | — | WO | claimed |
| EP-0809635-B1 | ALPHA-SUBSTITUTED HYDRAZIDES HAVING CALPAIN INHIBITORY ACTIVITY | WARNER LAMBERT CO (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-0809635-A1 | ALPHA-SUBSTITUTED HYDRAZIDES HAVING CALPAIN INHIBITORY ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025403-A1 | α-SUBSTITUTED HYDRAZIDES HAVING CALPAIN INHIBITORY ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1996-08-22 | — | — | WO | disclosed |