Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.50 |
| ▸ | GCGR | P47871 | 11/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784715 | 0.85 | HDAC1 (0.48) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL7784713 | 0.85 | HDAC1 (0.48) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL8842877 | 0.78 | PTP4A3 (0.51) | MCL1ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL7794250 | 0.78 | PTP4A3 (0.51) | MCL1ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL7793570 | 0.75 | MAPT (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8842878 | 0.74 | POLB (0.53) | HDAC1HDAC2HDAC8MCL1APP | |
| SCHEMBL7790430 | 0.74 | POLB (0.53) | HDAC1HDAC2HDAC8MCL1APP | |
| SCHEMBL8842889 | 0.73 | ALDH1A1 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7784722 | 0.73 | ALDH1A1 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7784710 | 0.72 | GAA (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723969-B1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AG (DE) | 2001-11-14 | — | — | EP | disclosed |
| US-5627173-A | Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0723969-A1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |