SCHEMBL393946

SCHEMBL393946

COCCO[Si](OCCOC)(OCCOC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.41
TSHR P16473 2/20 0.38
KCNH3 Q9ULD8 2/20 0.36
ALDH1A1 P00352 4/20 0.34
POLB P06746 2/20 0.34
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MPO P05164 1/20 0.33
NCF1 P14598 1/20 0.33
CA4 P22748 1/20 0.32
NR1I2 O75469 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1969360 0.92 CA2 (0.37) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL8678984 0.88 MAPK1 (0.39) CA2KCNH3ALDH1A1POLBLMNA
SCHEMBL5363348 0.83 CA2 (0.41) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL19356701 0.83 DUT (0.41) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL28808583 0.81 MEN1 (0.36) CA2KCNH3ALDH1A1POLBLMNA
SCHEMBL9880244 0.81 CA2 (0.40) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL9880245 0.81 CA2 (0.40) CA2TSHRKCNH3ALDH1A1POLB
SCHEMBL30130340 0.80 CA4 (0.33) CA2KCNH3POLBCA4
SCHEMBL105659 0.80 LMNA (0.39) ALDH1A1LMNAHPGDMEN1KMT2A
SCHEMBL11444489 0.79 NCF1 (0.40) TSHRALDH1A1TDP1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703866-B2 Room temperature curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-04-22 US claimed
EP-0862187-B1 Formulation for the insulating protection of electric conductors SERVICIOS CONDUMEX SA (MX) 2003-08-20 EP claimed
EP-3429980-B1 SURFACE APPLIED CORROSION INHIBITOR SIKA TECH AG (CH) 2026-05-13 EP disclosed
US-20260109109-A1 ADDITIVE MANUFACTURING GUIDE DOW GLOBAL TECHNOLOGIES LLC (US) 2026-04-23 US disclosed
EP-3600892-B1 METHOD OF FORMING POROUS THREE-DIMENSIONAL (3D) ARTICLE DOW SILICONES CORP (US) 2026-04-22 EP disclosed
US-12606672-B2 Curable composition DAIKIN INDUSTRIES, LTD. (JP) 2026-04-21 US disclosed
EP-3790725-B1 METHOD OF FORMING A THREE-DIMENSIONAL (3D) ARTICLE DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12508556-B2 Static mixer DOW SILICONES CORPORATION (US) 2025-12-30 US disclosed
EP-4660250-A1 ROOM-TEMPERATURE-CURABLE SILICONE COMPOSITION Momentive Performance Materials Japan LLC (JP) 2025-12-10 EP disclosed
US-12458932-B2 Filtration membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-11-04 US disclosed
EP-4079787-B1 CURABLE COMPOSITION DAIKIN IND LTD (JP) 2025-09-10 EP disclosed
EP-0074913-B1 SOLVENTLESS COMPOSITIONS OF POLYSILOXANES WITH HYDROXYSILYL GROUPS AND RETICULATING AGENTS WITH ALKOXYSILYL GROUPS CATALYZED BY ORGANIC IRON OR ZIRCONIUM COMPOUNDS, THEIR USE IN IMPREGNATING OR COATING COMPOSITIONS FOR ASBEST, CELLULOSIC OR SYNTHETIC MATERIALS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-08-20 EP disclosed
US-4543381-A Tree retardant additive composition for polymeric insulation NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1985-09-24 US disclosed
US-4404348-A Solventless organosilicon coating/impregnating compositions RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-09-13 US disclosed
EP-0074913-A1 Solventless compositions of polysiloxanes with hydroxysilyl groups and reticulating agents with alkoxysilyl groups catalyzed by organic iron or zirconium compounds, their use in impregnating or coating compositions for asbest, cellulosic or synthetic materials RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-03-23 EP disclosed
EP-0070786-A1 Process for preparing moisture-curable organopolysiloxane compositions by condensing organosilicen compounds having silicon-bound hydroxyl groups, alkoxy-silylated cross-linking agents and a substitituted hydroxyl amine; compositions and their use in obtaining cured materials RHONE-POULENC CHIMIE (FR) 1983-01-26 EP disclosed
US-4299713-A HIGH VOLTAGE CABLES NATIONAL DISTILLERS AND CHEMICAL CORP. (US) 1981-11-10 US disclosed
US-4143088-A ORGANOSILICON COMPOUND, ORGANOTITANIUM COMPOUND RHONE-POULENC INDUSTRIES (FR) 1979-03-06 US disclosed
US-4064096-A Curable, storage-stable liquid organopolysiloxane compositions RHONE-POULENC INDUSTRIES (FR) 1977-12-20 US disclosed
US-3965280-A Use of organopolysiloxane compositions which cure at ambient temperature in coating electrical and electronic devices RHONE-POULENC S.A. (FR) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606672-B2 Curable composition F8, CCNE2, PF4 CA2 213/4885TSHR 1580/4885KCNH3 1295/4885
US-12508556-B2 Static mixer CTNNA1, CTNND1, ARCN1 CA2 4391/4885TSHR 1859/4885KCNH3 3764/4885
US-20260109109-A1 ADDITIVE MANUFACTURING GUIDE HTR3D, SMCHD1, SMC3 CA2 3654/4885TSHR 3681/4885KCNH3 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.