Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789413 | 0.89 | RXFP1 (0.44) | ALDH1A1RXFP1KCNK3KCNK9GAA | |
| SCHEMBL7787169 | 0.86 | ALDH1A1 (0.58) | ALDH1A1RXFP1KCNK9GAALMNA | |
| SCHEMBL7785458 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL7784998 | 0.78 | MAPKAPK2 (0.41) | ALDH1A1KCNK3KCNK9GAALMNA | |
| SCHEMBL7784878 | 0.77 | ALDH1A1 (0.68) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL7787611 | 0.76 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7789410 | 0.75 | ALDH1A1 (0.57) | ALDH1A1RXFP1KCNK9GAALMNA | |
| SCHEMBL7785313 | 0.73 | GPR88 (0.49) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL7789059 | 0.71 | MAPKAPK2 (0.49) | GAAMEN1KMT2AMAPK1 | |
| SCHEMBL7780618 | 0.71 | MAPKAPK2 (0.42) | MEN1KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |