Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP5 | P51878 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8030850 | 0.99 | DRD2 (0.38) | DRD2SLC6A4CASP1CASP4CASP5 | |
| SCHEMBL7798296 | 0.81 | HTR7 (0.40) | CASP1CASP4CASP5HTR7ACHE | |
| Hydrochloric Acid SCHEMBL8162484 | 0.81 | HTR7 (0.40) | CASP1CASP4CASP5HTR7ACHE | |
| SCHEMBL7804156 | 0.80 | DRD2 (0.48) | DRD2SLC6A4DRD4DRD3ACHE | |
| SCHEMBL7802607 | 0.80 | HTR1D (0.47) | DRD2SLC6A4OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL8033624 | 0.79 | DRD2 (0.47) | DRD2SLC6A4DRD4DRD3ACHE | |
| Hydrochloric Acid SCHEMBL8033531 | 0.79 | HTR1A (0.46) | DRD2SLC6A4OPRM1OPRL1OPRK1 | |
| SCHEMBL7804305 | 0.77 | HTR1D (0.50) | DRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL7804169 | 0.77 | HTR1D (0.46) | DRD2SLC6A4DRD4HTR1DHTR1B | |
| SCHEMBL7798179 | 0.77 | HTR1D (0.46) | DRD2SLC6A4HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |