Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810746 | 0.89 | BCL9 (0.56) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7810069 | 0.83 | HSD11B1 (0.59) | NPC1RAB9AALDH1A1TSHRMEN1 | |
| SCHEMBL7804301 | 0.82 | KCNA5 (0.73) | MAPTKCNA5ALDH1A1GAAHTT | |
| SCHEMBL7814130 | 0.81 | LMNA (0.54) | ALDH1A1GAATSHRKDM4EEGLN1 | |
| SCHEMBL27303865 | 0.81 | MAPT (0.84) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7813604 | 0.80 | HSP90AA1 (0.46) | MAPTCYP3A4TSHREGLN1MEN1 | |
| SCHEMBL7804429 | 0.79 | HSD11B1 (0.66) | SMN1; SMN2ALDH1A1GAAEGLN1LMNA | |
| SCHEMBL7810206 | 0.79 | HSD11B1 (0.54) | SMN1; SMN2ALDH1A1GAATSHREGLN1 | |
| SCHEMBL7810110 | 0.78 | HSD11B1 (0.51) | GAATSHREGLN1MEN1KMT2A | |
| SCHEMBL7817580 | 0.78 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |