SCHEMBL7807703

SCHEMBL7807703

CC(C)(C)c1ccnc(-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 2/20 0.53
KIF11 P52732 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
HTR1A P08908 1/20 0.43
HTR7 P34969 1/20 0.43
METAP2 P50579 1/20 0.41
MIF P14174 1/20 0.40
AURKA O14965 1/20 0.40
HSP90AA1 P07900 1/20 0.40
PRKACA P17612 1/20 0.40
ADORA2A P29274 1/20 0.40
MAPKAPK2 P49137 1/20 0.40
PIM1 P11309 1/20 0.40
CYP2A6 P11509 1/20 0.40
NPC1 O15118 1/20 0.40
TRPV1 Q8NER1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31176227 1.00 ASIC3 (0.53) ASIC3KIF11MEN1KMT2AKDM4E
SCHEMBL18695526 0.98 ASIC3 (0.52) ASIC3KIF11MEN1KMT2AKDM4E
SCHEMBL25516950 0.92 ASIC3 (0.46) ASIC3KIF11MEN1KMT2AKDM4E
SCHEMBL31695223 0.90 KIF11 (0.43) ASIC3KIF11KMT2AKDM4EALDH1A1
SCHEMBL27344642 0.90 KIF11 (0.43) ASIC3KIF11KMT2AKDM4EALDH1A1
SCHEMBL2481424 0.90 KIF11 (0.53) ASIC3KIF11MEN1KMT2AMETAP2
SCHEMBL26206984 0.89 ASIC3 (0.44) ASIC3KIF11MEN1KMT2AKDM4E
SCHEMBL26471845 0.89 KIF11 (0.50) ASIC3KIF11METAP2CYP2A6
SCHEMBL15991694 0.88 KIF11 (0.51) ASIC3KIF11METAP2MAPKAPK2TGFBR1
SCHEMBL28790717 0.88 KIF11 (0.51) ASIC3KIF11MEN1KMT2AMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111533684-A Method for alkenylating pyridine compound 四川大学 2020-08-14 CN claimed
CN-104356053-A Preparation method of 2-(3-halogen phenyl) pyridine derivative UNIV TIANJIN 2015-02-18 CN claimed
US-12404290-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-09-02 US disclosed
US-20250179104-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2025-06-05 US disclosed
US-20250042928-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-02-06 US disclosed
US-20250002778-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-01-02 US disclosed
US-20240425538-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-12-26 US disclosed
US-20240415003-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-12-12 US disclosed
EP-4467555-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-11-27 EP disclosed
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-11 US disclosed
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-11 US disclosed
US-7741281-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2010-06-22 US disclosed
US-20100099684-A1 Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands BRISTOL-MYERS SQUIBB COMPANY 2010-04-22 US disclosed
US-20090270405-A1 QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS BRISTOL-MYERS SQUIBB COMPANY 2009-10-29 US disclosed
CN-100445294-C Platinum complex and luminescent element TAKASAGO PERFUMERY CO LTD (JP) 2008-12-24 CN disclosed
US-20080107623-A1 Inhibitors of Hepatitis C Virus BRISTOL-MYERS SQUIBB COMPANY 2008-05-08 US disclosed
US-20080107625-A1 Inhibitors of Hepatitis C Virus BRISTOL-MYERS SQUIBB COMPANY 2008-05-08 US disclosed
US-20080107624-A1 Inhibitors of Hepatitis C Virus BRISTOL-MYERS SQUIBB COMPANY 2008-05-08 US disclosed
US-20070099825-A1 ethyl 2-(biphenyl-4-yl)-6-(tert-butoxycarbonylamino)-2-methoxy-8-(2-nitrophenylsulfonyl)-5,16-dioxo-1,2,3,5,6,7,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[n]pyrrolo[2,1-c][1,4,8]triazacyclopentadecine-14a-carboxylate; viricide; synergistic with other active ingredients BRISTOL-MYERS SQUIBB COMPANY 2007-05-03 US disclosed
US-20070099825-A1 ethyl 2-(biphenyl-4-yl)-6-(tert-butoxycarbonylamino)-2-methoxy-8-(2-nitrophenylsulfonyl)-5,16-dioxo-1,2,3,5,6,7,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[n]pyrrolo[2,1-c][1,4,8]triazacyclopentadecine-14a-carboxylate; viricide; synergistic with other active ingredients BRISTOL-MYERS SQUIBB COMPANY 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099684-A1 Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands CHRNA7, CHRNA5, CHRNA6 ASIC3 1435/4885KIF11 3578/4885MEN1 3838/4885
US-20240425538-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OPRD1 ASIC3 2422/4885KIF11 2450/4885MEN1 2698/4885
US-20250042928-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, NPY1R, OCIAD1 ASIC3 2089/4885KIF11 2919/4885MEN1 3678/4885
US-20080107623-A1 Inhibitors of Hepatitis C Virus HAVCR2, HCCS, VIP ASIC3 4246/4885KIF11 4212/4885MEN1 3909/4885
US-20240415003-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, POF1B ASIC3 3130/4885KIF11 1595/4885MEN1 1748/4885
US-20070099825-A1 ethyl 2-(biphenyl-4-yl)-6-(tert-butoxycarbonylamino)-2-methoxy-8-(2-nitrophenylsulfonyl)-5,16-dioxo-1,2,3,5,6,7,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[n]pyrrolo[2,1-c][1,4,8]triazacyclopentadecine-14a-carboxylate; viricide; synergistic with other active ingredients TERT, VIP, YWHAZ ASIC3 4725/4885KIF11 3633/4885MEN1 4760/4885
US-20080107624-A1 Inhibitors of Hepatitis C Virus HAVCR2, MRPS23, HCCS ASIC3 3671/4885KIF11 4204/4885MEN1 3911/4885
US-20090270405-A1 QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS CHRNA7, CHRNA5, CHRNA6 ASIC3 1435/4885KIF11 3578/4885MEN1 3838/4885
US-20080107625-A1 Inhibitors of Hepatitis C Virus HAVCR2, HCCS, VIP ASIC3 4246/4885KIF11 4212/4885MEN1 3909/4885
US-20250179104-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT TPR, OCIAD1, OCIAD2 ASIC3 1662/4885KIF11 3018/4885MEN1 1454/4885
US-12404290-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device L1CAM, MSL1, EML4 ASIC3 3686/4885KIF11 2755/4885MEN1 14/4885
US-20240237507-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, MSL1, EML4 ASIC3 3686/4885KIF11 2755/4885MEN1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.