Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483736 | 0.73 | — | — | |
| SCHEMBL23633181 | 0.72 | MTNR1A (0.35) | — | |
| SCHEMBL2965379 | 0.70 | NTSR1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11815728 | 0.65 | PTGS2 (0.59) | TDP1ELANEPTGS2MEN1KMT2A | |
| SCHEMBL191429 | 0.65 | ACMSD (0.49) | TDP1ELANEPTGS2MEN1KMT2A | |
| SCHEMBL8380044 | 0.65 | ACMSD (0.49) | TDP1ELANEPTGS2MEN1KMT2A | |
| SCHEMBL14971441 | 0.65 | TDP1 (0.44) | TDP1ALDH1A1CYP3A4ELANEPTGS2 | |
| SCHEMBL13189924 | 0.65 | MAOA (0.40) | — | |
| SCHEMBL312110 | 0.65 | MMP3 (0.41) | MEN1KMT2A | |
| SCHEMBL29658186 | 0.64 | DRD2 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841337-B1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |
| EP-0841337-A1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |