Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918799 | 0.82 | MAPT (0.39) | LMNAKMT2APOLBMAPTMAPK1 | |
| SCHEMBL7828312 | 0.80 | ALDH1A1 (0.41) | KMT2AMAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL27214951 | 0.78 | LTA4H (0.42) | LMNAKMT2AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL7830178 | 0.77 | CA1 (0.46) | LMNAKMT2ATP53MAPTMAPK1 | |
| SCHEMBL1675994 | 0.74 | TSHR (0.46) | LMNAKMT2AMAPK1HTTNCOA1 | |
| SCHEMBL5506330 | 0.72 | MAOA (0.51) | LMNAKMT2ATP53POLBMAPT | |
| SCHEMBL7827640 | 0.72 | — | — | |
| SCHEMBL7815949 | 0.72 | PDK2 (0.46) | KMT2AMAPTNPSR1GAAPTGS2 | |
| SCHEMBL11859777 | 0.72 | HNF4A (0.37) | MAPK1DPP4 | |
| SCHEMBL11833811 | 0.71 | NCOA1 (0.53) | LMNAKMT2AMAPK1HTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213324-A1 | COLORING COMPOSITION CONTAINING ISOINDOLINE COMPOUND AND USE OF SAME | TOYO INK SC HOLDINGS CO., LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-3960824-A1 | COLORING COMPOSITION CONTAINING ISOINDOLINE COMPOUND AND USE OF SAME | Toyo Ink SC Holdings Co., Ltd. (JP) | 2022-03-02 | — | — | EP | disclosed |
| CN-113710758-A | Coloring composition containing isoindoline compound and use thereof | 东洋油墨SC控股株式会社 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020218262-A1 | COLORING COMPOSITION CONTAINING ISOINDOLINE COMPOUND AND USE OF SAME | 東洋インキＳＣホールディングス株式会社 | 2020-10-29 | — | — | WO | disclosed |
| EP-0679640-B1 | Carboxylate and heat-sensitive recording material using same | MITSUI CHEMICALS INC (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0679640-A1 | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-11-02 | — | — | EP | disclosed |