Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219807 | 0.84 | MAPT (0.80) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL13401359 | 0.77 | KMT2A (0.70) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL13219539 | 0.76 | KCNMA1 (0.79) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL6635707 | 0.73 | SMN1; SMN2 (0.69) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL23011784 | 0.72 | PKM (0.68) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL22983097 | 0.70 | PKM (0.66) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL23011777 | 0.70 | PKM (0.79) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL13219574 | 0.70 | MAPT (1.00) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL16179844 | 0.70 | SIRT6 (1.00) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL23011774 | 0.70 | ALDH1A1 (0.84) | KMT2AMEN1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |