Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196920 | 1.00 | LMNA (0.62) | LMNAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL196919 | 1.00 | LMNA (0.62) | LMNAMAPK1HDAC3HDAC4HDAC1 | |
| Fluoride SCHEMBL28879249 | 0.98 | LMNA (0.60) | LMNAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL8997409 | 0.94 | LMNA (0.56) | LMNAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL275597 | 0.87 | LMNA (0.79) | LMNAMAPK1NPSR1BLMTSHR | |
| SCHEMBL19735013 | 0.79 | HDAC3 (0.45) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11218186 | 0.79 | HDAC3 (0.45) | LMNAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL4092644 | 0.79 | HDAC3 (0.45) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL531658 | 0.79 | HDAC3 (0.45) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28795451 | 0.79 | HPGD (0.48) | LMNAMAPK1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-4001279-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114524821-A | Novel spiropyrrolidine derived antiviral drugs | 英安塔制药有限公司 | 2022-05-24 | — | — | CN | disclosed |
| US-10857517-B2 | Porous chiral materials and uses thereof | NANKAI UNIVERSITY (CN) | 2020-12-08 | — | — | US | disclosed |
| EP-3196185-B1 | ASYMMETRICAL HYDROGENATION REACTION OF KETONIC ACID COMPOUND | ZHEJIANG JIUZHOU PHARMA SCIENCE & TECH CO LTD (CN) | 2019-06-12 | — | — | EP | disclosed |
| US-20170260119-A1 | Asymmetrical hydrogenation reaction of ketonic acid compound | ZHEJIANG JIUZHOU PHARMA SCIENCE&TECHNOLOGY CO LTD (CN) | 2017-09-14 | — | — | US | disclosed |
| US-20170260119-A1 | Asymmetrical hydrogenation reaction of ketonic acid compound | ZHEJIANG JIUZHOU PHARMA SCIENCE&TECHNOLOGY CO LTD (CN) | 2017-09-14 | — | — | US | disclosed |
| EP-3196185-A1 | ASYMMETRICAL HYDROGENATION REACTION OF KETONIC ACID COMPOUND | Zhejiang Jiuzhou Pharma Science & Technology Co., Ltd. (CN) | 2017-07-26 | — | — | EP | disclosed |
| US-9315792-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-7521216-B2 | Nitrilases and methods for making and using them | VERENIUM CORPORATION (US) | 2009-04-21 | — | — | US | disclosed |
| EP-2039762-A2 | Nitralases | Verenium Corporation (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20080311636-A1 | Method for Producing Optically Active Alpha-Hydroxycarboxylic Acid | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080311636-A1 | Method for Producing Optically Active Alpha-Hydroxycarboxylic Acid | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| US-20080311636-A1 | Method for Producing Optically Active Alpha-Hydroxycarboxylic Acid | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1930441-A1 | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE -HYDROXYCARBOXYLIC ACID | Daiichi Fine Chemical Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4172196-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4112228-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-3985738-A | ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311636-A1 | Method for Producing Optically Active Alpha-Hydroxycarboxylic Acid | PCCA, HCAR1, HCAR2 | LMNA 640/4885MAPK1 3203/4885HDAC3 4252/4885 |
| US-20170260119-A1 | Asymmetrical hydrogenation reaction of ketonic acid compound | KHK, PKLR, BCKDK | LMNA 3213/4885MAPK1 1240/4885HDAC3 1394/4885 |
| US-10857517-B2 | Porous chiral materials and uses thereof | ANXA7, XDH, OPRM1 | LMNA 219/4885MAPK1 1200/4885HDAC3 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.