Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826292 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7827211 | 0.83 | HSD17B10 (0.51) | PARP15PARP10TNKS2PDE3BPDE3A | |
| SCHEMBL8067091 | 0.82 | ULK1 (0.34) | ULK1PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL7826811 | 0.81 | ALDH1A1 (0.40) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL8058133 | 0.81 | KMT2A (0.40) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL7828142 | 0.81 | TBK1 (0.47) | KDM4ELRRK2 | |
| SCHEMBL7826517 | 0.80 | MAOA (0.52) | KDM4EALDH1A1HPGDHSD17B10LRRK2 | |
| SCHEMBL7824709 | 0.80 | PDE2A (0.41) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7823420 | 0.80 | DYRK1A (0.44) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7827947 | 0.79 | PTGES (0.43) | KDM4EALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |