Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.38 |
| ▸ | MMP1 | P03956 | 15/20 | 0.38 |
| ▸ | MMP9 | P14780 | 15/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 10/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316088 | 0.84 | MMP13 (0.45) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL7820104 | 0.84 | MMP13 (0.45) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL7830182 | 0.83 | TRPM8 (0.48) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL7453309 | 0.80 | MEN1 (0.44) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL7820002 | 0.79 | PTGS2 (0.41) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL7323574 | 0.76 | LMNA (0.43) | MMP13MMP1MMP9ADAM17TRPM8 | |
| SCHEMBL7319845 | 0.76 | PTGS2 (0.41) | MMP13MMP1MMP9ADAM17TRPM8 | |
| SCHEMBL7318219 | 0.74 | MMP13 (0.56) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL6815791 | 0.72 | MMP13 (0.60) | MMP13MMP1MMP9ADAM17MMP12 | |
| SCHEMBL7820004 | 0.72 | TAS1R3 (0.43) | MMP13MMP1MMP9ADAM17MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938471-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2001-12-12 | — | — | EP | claimed |