Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845849 | 0.88 | MAPK1 (0.32) | CYP1A2CYP2C19CYP19A1 | |
| SCHEMBL7837398 | 0.86 | ALDH1A1 (0.36) | CYP1A2CYP2C19CYP19A1MEN1KMT2A | |
| SCHEMBL7845581 | 0.86 | ALDH1A1 (0.34) | POLBCYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL7846879 | 0.85 | CA1 (0.38) | TBXA2RPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7848540 | 0.83 | TBXA2R (0.37) | TBXA2RPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7845066 | 0.82 | CYP1A2 (0.36) | TBXA2RPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7845258 | 0.73 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7845061 | 0.72 | BAZ1A (0.36) | TBXA2RCYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL7837573 | 0.72 | ENPP1 (0.33) | CYP1A2CYP3A4CYP2C19CYP19A1MEN1 | |
| SCHEMBL7849223 | 0.71 | SLC10A2 (0.35) | TBXA2RCYP1A2CYP2C19CYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |