Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652644 | 0.79 | ALDH1A1 (0.61) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL9726458 | 0.78 | ALDH1A1 (0.67) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL80182 | 0.76 | ALDH1A1 (0.64) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL80183 | 0.76 | ALDH1A1 (0.64) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL103586 | 0.76 | ALDH1A1 (1.00) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL19998299 | 0.76 | ALDH1A1 (0.64) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL9681770 | 0.75 | DPP4 (0.58) | ALDH1A1FEN1NPC1TSHRPBRM1 | |
| SCHEMBL2092585 | 0.74 | ALDH1A1 (0.61) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL320037 | 0.74 | ALDH1A1 (0.61) | ALDH1A1FEN1HPGDNPC1GLA | |
| Hydrochloric Acid SCHEMBL8042412 | 0.74 | ALDH1A1 (0.61) | ALDH1A1FEN1HPGDNPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | claimed |
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | claimed |
| EP-3039018-B1 | PYRIDYL CARBOXAMIDE DERIVATIVES WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | claimed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | claimed |
| EP-3073827-A1 | NEW PESTICIDAL COMPOUNDS AND USES | Bayer Animal Health GmbH (DE) | 2016-10-05 | — | — | EP | claimed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | claimed |
| EP-3039018-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | Bayer CropScience Aktiengesellschaft (DE) | 2016-07-06 | — | — | EP | claimed |
| CN-105658638-A | compounds with insecticidal activity | 拜耳作物科学股份公司 | 2016-06-08 | — | — | CN | claimed |
| EP-2606727-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | claimed |
| EP-2606728-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | claimed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | claimed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | claimed |
| EP-2589294-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | claimed |
| EP-2589292-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | claimed |
| EP-1885712-B1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE AG (DE) | 2011-02-23 | — | — | EP | claimed |
| EP-1383750-B1 | UREA DERIVATIVES AS INTEGRIN ALPHA 4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-26 | — | — | EP | claimed |
| EP-1740544-B1 | 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2007-09-19 | — | — | EP | claimed |
| US-4942232-A | FOR PRINTING AND DYEING CELLULOSE FIBERS | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | KDM5C, KDM5B, KDM5A | ALDH1A1 2449/4885FEN1 1749/4885HPGD 2031/4885 |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | ALDH1A1 1603/4885FEN1 4352/4885HPGD 1289/4885 |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | ACHE, DDT, CAT | ALDH1A1 929/4885FEN1 4135/4885HPGD 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.