Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 3/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7733824 | 0.82 | MMP2 (0.39) | MMP2CTSCLNPEPERAP2ERAP1 | |
| SCHEMBL7733828 | 0.79 | DAGLA (0.38) | MMP2CTSCLNPEPERAP2ERAP1 | |
| SCHEMBL7730721 | 0.79 | LTA4H (0.40) | MMP2LNPEPERAP2ERAP1LTA4H | |
| Trifluoroacetic Acid SCHEMBL7731056 | 0.78 | PRSS1 (0.38) | MMP2LNPEPLTA4HPRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7735541 | 0.77 | CCR3 (0.41) | MMP2CTSCLNPEPERAP2ERAP1 | |
| SCHEMBL7735983 | 0.76 | RAB9A (0.44) | KMT2ATSHR | |
| SCHEMBL10084246 | 0.75 | ZAP70 (0.37) | MMP2PRSS1PRSS2PRSS3TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL7732324 | 0.74 | SLC7A11 (0.37) | MMP2CTSCLTA4HPRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.73 | RAB9A (0.41) | KMT2ATSHR | |
| SCHEMBL7857980 | 0.72 | LNPEP (0.55) | MMP2CTSCLNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |