Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 8/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7732364 | 0.93 | PRSS1 (0.40) | PRSS1PRSS2PRSS3TPSAB1LTA4H | |
| Trifluoroacetic Acid SCHEMBL7735541 | 0.93 | CCR3 (0.41) | PRSS1PRSS2PRSS3TPSAB1MAPT | |
| Trifluoroacetic Acid SCHEMBL7733824 | 0.90 | MMP2 (0.39) | LTA4HMMP2DAGLALNPEP | |
| SCHEMBL7733828 | 0.88 | DAGLA (0.38) | LTA4HMMP2DAGLALNPEP | |
| Trifluoroacetic Acid SCHEMBL7732324 | 0.82 | SLC7A11 (0.37) | PRSS1PRSS2PRSS3TPSAB1LTA4H | |
| SCHEMBL7732329 | 0.80 | ZAP70 (0.34) | PRSS1PRSS2PRSS3TPSAB1LTA4H | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.80 | RAB9A (0.41) | MAPT | |
| Trifluoroacetic Acid SCHEMBL8360682 | 0.78 | LNPEP (0.35) | LTA4HLNPEP | |
| SCHEMBL7861009 | 0.78 | MMP2 (0.40) | PRSS1PRSS2PRSS3TPSAB1LTA4H | |
| SCHEMBL7723171 | 0.76 | MAPT (0.56) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |