Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690288 | 0.85 | MCL1 (0.41) | ALDH1A1MEN1MAPTKMT2ASLC9A1 | |
| SCHEMBL787663 | 0.75 | HSD11B1 (0.43) | ALDH1A1MEN1POLBGAAMAPT | |
| SCHEMBL2387694 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MEN1POLBGAAMAPT | |
| SCHEMBL4160530 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1POLBGAAMAPT | |
| SCHEMBL1260293 | 0.69 | CA2 (0.42) | MAPTSLC9A1 | |
| SCHEMBL27850397 | 0.68 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL4790575 | 0.68 | L3MBTL1 (0.46) | PKMMEN1GAAKMT2A | |
| SCHEMBL4272799 | 0.67 | MCL1 (0.51) | PKMALDH1A1GAA | |
| SCHEMBL5446748 | 0.66 | KEAP1 (0.56) | KEAP1NFE2L2ALDH1A1MEN1MAPT | |
| SCHEMBL22857621 | 0.66 | TRPA1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-A2 | SULFONAMIDE COMPOUNDS | Kancera AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035171-A2 | NEW COMPOUNDS | KANCERA AB (SE) | 2012-03-22 | — | — | WO | disclosed |