Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790572 | 0.78 | LIMK1 (0.42) | CA2CA1SLC9A1CA12CA9 | |
| SCHEMBL1575935 | 0.73 | HSD11B1 (0.44) | CA2CA1CA4CA12CA7 | |
| SCHEMBL21234346 | 0.70 | GPR3 (0.39) | CA2SLC9A1CA12CA9MAPT | |
| SCHEMBL1260771 | 0.69 | PTGS2 (0.34) | CA2CA1CA6CA12CA7 | |
| SCHEMBL788101 | 0.69 | PKM (0.33) | SLC9A1MAPT | |
| SCHEMBL4790575 | 0.68 | L3MBTL1 (0.46) | CA2CA1CA4CA6CA12 | |
| SCHEMBL3816392 | 0.68 | LMNA (0.48) | MAPT | |
| SCHEMBL19502377 | 0.68 | TUBB4A (0.31) | — | |
| SCHEMBL3690288 | 0.68 | MCL1 (0.41) | SLC9A1MAPTPFKFB3PFKFB4 | |
| SCHEMBL22909023 | 0.66 | ALDH1A1 (0.56) | CA2CA1CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011022207-A1 | BIS-SULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-02-24 | — | — | WO | disclosed |