Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898631 | 0.82 | MEN1 (0.48) | MEN1KMT2ANPC1PIN1ALDH1A1 | |
| SCHEMBL9810832 | 0.75 | SMN1; SMN2 (0.44) | MEN1KMT2ANPC1PIN1ALDH1A1 | |
| SCHEMBL9508600 | 0.74 | TRPM8 (0.47) | ALDH1A1MAPTLMNAHPGDPGR | |
| SCHEMBL15787845 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10HPGDCA12 | |
| SCHEMBL28320439 | 0.74 | TRPM8 (0.45) | ALDH1A1MAPTLMNAL3MBTL1POLB | |
| SCHEMBL4667859 | 0.73 | TRPM8 (0.47) | ALDH1A1MAPTLMNAL3MBTL1POLB | |
| SCHEMBL12272832 | 0.71 | DGAT1 (0.43) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7371261 | 0.71 | TRPM8 (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL16050447 | 0.70 | MEN1 (0.54) | MEN1KMT2ANPC1PIN1ALDH1A1 | |
| SCHEMBL31388076 | 0.70 | ADRA2C (0.43) | ALDH1A1MAPTL3MBTL1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191284-B1 | A FERROCENEYLPHOSPHINE LIGAND AND COMPLEXES USEFUL FOR HOMOGENEOUS CATALYTIC ENANTIOSELECTIVE HYDROGENATION | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |