Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 3/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023013 | 0.79 | MMP9 (0.37) | MMP9SORT1CALM1MEN1ELANE | |
| SCHEMBL11125426 | 0.74 | CTRB1 (0.38) | MMP9SORT1TSHRCALM1MEN1 | |
| SCHEMBL7895962 | 0.72 | USP1 (0.38) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7894646 | 0.68 | HPGD (0.38) | SORT1HPGDTSHRCALM1MEN1 | |
| SCHEMBL8132266 | 0.61 | CALM1 (0.55) | SORT1CALM1MEN1ELANEKMT2A | |
| SCHEMBL15282017 | 0.60 | TAAR1 (0.40) | MMP9CALM1MAPT | |
| SCHEMBL304780 | 0.60 | TP53 (0.44) | SORT1CALM1ELANELMNACTRC | |
| SCHEMBL305339 | 0.59 | CALM1 (0.52) | SORT1CALM1MEN1ELANEKMT2A | |
| SCHEMBL22618564 | 0.59 | CTRB1 (0.50) | LMNAPLA2G6PLA2G4A | |
| SCHEMBL10973500 | 0.59 | CES2 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180374-B1 | ENANTIOMORPHS; BIOTRANSFORMATION USING ENZYME IN PRESENCE OF AN ALCOHOL OF AN AZLACTONE | CHIROTECH TECHNOLOGY, INC. (GB) | 2001-01-30 | — | — | US | disclosed |
| EP-0726891-B1 | A METHOD FOR PREPARING TERT-LEUCINE AND ANALOGUES THEREOF IN ENANTIOMERIC FORM, AND INTERMEDIATES THEREIN | CHIROTECH TECHNOLOGY LTD (GB) | 1999-02-03 | — | — | EP | disclosed |