Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701020 | 0.84 | P2RY12 (0.43) | — | |
| SCHEMBL4698338 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7900328 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7901896 | 0.81 | GAA (0.44) | MEN1KMT2A | |
| SCHEMBL4701810 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL4702813 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7900498 | 0.76 | CCR1 (0.46) | SMN1; SMN2 | |
| SCHEMBL4698653 | 0.75 | LMNA (0.47) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7904100 | 0.75 | ITGB3 (0.41) | LMNA | |
| SCHEMBL7892907 | 0.74 | KMT2A (0.43) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |