Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901896 | 0.88 | GAA (0.44) | KMT2AMEN1GAATACR1RORC | |
| SCHEMBL4701020 | 0.84 | P2RY12 (0.43) | GAATAS1R3TAS1R1 | |
| SCHEMBL7900104 | 0.83 | APOBEC3A (0.47) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL7900498 | 0.82 | CCR1 (0.46) | GAATAS1R3TAS1R1 | |
| SCHEMBL7904100 | 0.81 | ITGB3 (0.41) | LMNAGAARORCTAS1R3TAS1R1 | |
| SCHEMBL4698653 | 0.81 | LMNA (0.47) | ALDH1A1LMNAGAACYP2D6CYP2C9 | |
| SCHEMBL4702813 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL7892907 | 0.80 | KMT2A (0.43) | ALDH1A1KMT2AMEN1GAAKDM4E | |
| SCHEMBL7892913 | 0.80 | ITGB3 (0.40) | ALDH1A1LMNAGAATAS1R3TAS1R1 | |
| SCHEMBL4701238 | 0.79 | PKM (0.45) | ALDH1A1KMT2AMEN1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |