Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702813 | 0.89 | ALDH1A1 (0.45) | LMNAALDH1A1GAAITGB3ITGA2B | |
| SCHEMBL4701238 | 0.87 | PKM (0.45) | ALDH1A1GAAITGB3ITGA2BHPGD | |
| SCHEMBL7900498 | 0.83 | CCR1 (0.46) | GAAITGB3ITGA2BITGAVF2R | |
| SCHEMBL4701810 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAAITGB3ITGA2BITGAV | |
| SCHEMBL4701020 | 0.82 | P2RY12 (0.43) | GAAITGB3ITGA2BITGAVTAS1R3 | |
| SCHEMBL4698338 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1GAACYP2D6CYP2C9 | |
| SCHEMBL7892913 | 0.81 | ITGB3 (0.40) | LMNAALDH1A1GAAITGB3ITGA2B | |
| SCHEMBL7955769 | 0.80 | HPGD (0.47) | GAAITGB3ITGA2BITGAVHPGD | |
| SCHEMBL7904100 | 0.80 | ITGB3 (0.41) | LMNAGAAITGB3ITGA2BITGAV | |
| SCHEMBL20530282 | 0.80 | POLB (0.46) | GAAITGB3ITGA2BITGAVHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |