Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 11/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698338 | 0.84 | ALDH1A1 (0.47) | TAS1R3TAS1R1GAA | |
| SCHEMBL7900104 | 0.84 | APOBEC3A (0.47) | — | |
| SCHEMBL7900498 | 0.83 | CCR1 (0.46) | TAS1R3TAS1R1GAAITGB3ITGA2B | |
| SCHEMBL4698653 | 0.82 | LMNA (0.47) | TAS1R3TAS1R1GAAITGB3ITGA2B | |
| SCHEMBL7904100 | 0.82 | ITGB3 (0.41) | TAS1R3TAS1R1GAAITGB3ITGA2B | |
| SCHEMBL7900328 | 0.81 | ALDH1A1 (0.43) | GAAITGB3ITGAV | |
| SCHEMBL4702813 | 0.81 | ALDH1A1 (0.45) | TAS1R3TAS1R1GAAITGB3ITGA2B | |
| SCHEMBL7901896 | 0.81 | GAA (0.44) | TAS1R3TAS1R1GAAITGB3ITGA2B | |
| SCHEMBL7892913 | 0.81 | ITGB3 (0.40) | TAS1R3TAS1R1GAAITGB3ITGA2B | |
| SCHEMBL4701810 | 0.81 | ALDH1A1 (0.44) | GAAITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |