Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910522 | 0.82 | KCNE1 (0.43) | CTSDBACE1KCNE1KCNQ1HRH3 | |
| SCHEMBL7900351 | 0.79 | KCNE1 (0.41) | KCNE1KCNQ1HRH3MAPTALDH1A1 | |
| SCHEMBL6601023 | 0.75 | KCNE1 (0.53) | KCNE1KCNQ1HRH3PTPN1KCNH2 | |
| SCHEMBL7910119 | 0.74 | CTSD (0.38) | CTSDBACE1KCNE1KCNQ1HRH3 | |
| SCHEMBL7464900 | 0.74 | KCNE1 (0.52) | CTSDBACE1KCNE1KCNQ1SIRT2 | |
| SCHEMBL7910107 | 0.74 | SIRT2 (0.43) | CTSDBACE1KCNE1KCNQ1SIRT2 | |
| SCHEMBL6602327 | 0.74 | KCNE1 (0.48) | KCNE1KCNQ1HRH3MAPTALDH1A1 | |
| SCHEMBL7906983 | 0.73 | MAPT (0.39) | KCNE1KCNQ1HRH3MAPTALDH1A1 | |
| SCHEMBL6601925 | 0.71 | KCNE1 (0.44) | KCNE1KCNQ1HRH3MAPTALDH1A1 | |
| SCHEMBL7470852 | 0.71 | KCNE1 (0.47) | KCNE1KCNQ1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |