Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LIMK2 | P53671 | 5/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898152 | 0.90 | HTT (0.51) | NR3C1ALDH1A1LIMK2LIMK1MEN1 | |
| SCHEMBL7715239 | 0.88 | LIMK2 (0.43) | NR3C1ALDH1A1SMN1; SMN2LIMK2LIMK1 | |
| SCHEMBL7715230 | 0.86 | LIMK2 (0.56) | ALDH1A1SMN1; SMN2LIMK2LIMK1MEN1 | |
| SCHEMBL7711039 | 0.81 | RAB9A (0.43) | ALDH1A1SMN1; SMN2LIMK2LIMK1MEN1 | |
| SCHEMBL10894219 | 0.69 | NR3C1 (0.87) | NR3C1NR3C2 | |
| SCHEMBL14354039 | 0.68 | NR3C1 (0.50) | NR3C1ALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL14354040 | 0.68 | NR3C1 (0.50) | NR3C1ALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL6840090 | 0.67 | ALDH1A1 (0.77) | NR3C1ALDH1A1SMN1; SMN2POLBNR3C2 | |
| SCHEMBL11705518 | 0.67 | CA1 (0.71) | ALDH1A1SMN1; SMN2POLBKMT2AHPGD | |
| SCHEMBL11949259 | 0.67 | SMN1; SMN2 (0.61) | NR3C1ALDH1A1SMN1; SMN2LIMK2LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123822-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING PYRIDAZINE SULFONAMIDE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2010-10-28 | — | — | WO | disclosed |