Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898403 | 0.93 | MMP2 (0.45) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7516046 | 0.82 | MMP13 (0.48) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7513672 | 0.82 | MMP13 (0.59) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7454044 | 0.75 | MMP2 (0.49) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7550995 | 0.75 | MMP13 (0.44) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7509339 | 0.74 | MMP13 (0.61) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7595438 | 0.73 | MMP13 (0.57) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7446582 | 0.73 | L3MBTL1 (0.47) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7509695 | 0.71 | MMP2 (0.58) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7389414 | 0.69 | MMP3 (0.54) | MMP13MMP3MMP1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |