Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.35 |
| ▸ | CHRNG | P07510 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913938 | 0.85 | CA2 (0.48) | KMT2A | |
| SCHEMBL119413 | 0.78 | POLB (0.55) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL29457845 | 0.78 | POLB (0.55) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL533063 | 0.75 | ALDH1A1 (0.55) | KMT2ALMNASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6888383 | 0.75 | LMNA (0.54) | LMNASMN1; SMN2F2PRSS1PRSS2 | |
| SCHEMBL9366959 | 0.74 | CES2 (0.62) | KMT2ASMN1; SMN2PRSS1PRSS2PRSS3 | |
| SCHEMBL7912398 | 0.74 | HSD11B1 (0.46) | KMT2ALMNASMN1; SMN2F2PRSS1 | |
| SCHEMBL29792725 | 0.73 | F2 (0.57) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL30525020 | 0.73 | ALDH1A1 (0.46) | KMT2ALMNASMN1; SMN2F2PRSS1 | |
| SCHEMBL35218 | 0.73 | ALDH1A1 (0.46) | KMT2ALMNASMN1; SMN2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |
| EP-0842148-B1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SANOFI SYNTHELABO (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0842148-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006136-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1997-02-20 | — | — | WO | disclosed |