Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790621 | 0.92 | KDR (0.46) | KDRF10MEN1KMT2AALDH1A1 | |
| SCHEMBL789915 | 0.88 | RAB9A (0.50) | KDRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL790392 | 0.87 | KDR (0.48) | KDRRAB9AMAPTLMNA | |
| SCHEMBL790093 | 0.85 | SMN1; SMN2 (0.48) | KDRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL790416 | 0.85 | MRGPRX4 (0.50) | KDRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL791199 | 0.83 | RAB9A (0.50) | KDRRAB9ALMNASTAT6 | |
| SCHEMBL791145 | 0.81 | KDR (0.46) | KDRMEN1KMT2ARAB9AMAPT | |
| SCHEMBL807273 | 0.80 | ALDH1A1 (0.53) | ALDH1A1RAB9AHPGDHSD17B10GBA1 | |
| Formic Acid SCHEMBL790534 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10GBA1GLA | |
| SCHEMBL789889 | 0.77 | RAB9A (0.48) | KDRRAB9ASTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |