Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.50 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905121 | 0.92 | ITGA4 (0.42) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7908666 | 0.91 | ITGB1 (0.52) | ITGB1ITGA4 | |
| SCHEMBL7896693 | 0.90 | ITGB1 (0.47) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7908862 | 0.89 | ALDH1A1 (0.46) | ITGB1ITGA4 | |
| SCHEMBL7905211 | 0.88 | ITGB1 (0.43) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7896690 | 0.87 | ITGB1 (0.42) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7896749 | 0.86 | ITGA4 (0.52) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7906197 | 0.86 | CCR2 (0.44) | ITGB1ITGA4 | |
| SCHEMBL7902838 | 0.85 | ITGB1 (0.43) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7896707 | 0.84 | GAA (0.45) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | claimed |
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |