Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 2/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905121 | 0.90 | ITGA4 (0.42) | ITGB3ITGAVITGA2BITGA4ITGB1 | |
| SCHEMBL7906194 | 0.87 | ITGA4 (0.41) | ITGB3ITGAVITGA2BITGA4ITGB1 | |
| SCHEMBL7905098 | 0.86 | ITGB1 (0.50) | ITGA4ITGB1 | |
| SCHEMBL7908666 | 0.84 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL7896620 | 0.84 | DPP4 (0.35) | TPH1WEE1OPRM1OPRD1OPRK1 | |
| SCHEMBL7896693 | 0.83 | ITGB1 (0.47) | ITGB3ITGAVITGA2BITGA4ITGB1 | |
| SCHEMBL6934214 | 0.83 | ITGB3 (0.39) | ITGB3ITGA2BOPRM1OPRD1OPRK1 | |
| SCHEMBL7906163 | 0.83 | L3MBTL1 (0.36) | ITGB3ITGAVITGA2BITGB1OPRM1 | |
| SCHEMBL7709457 | 0.82 | NOS3 (0.43) | ITGB3ITGAVITGA2BITGA4ITGB1 | |
| SCHEMBL7908862 | 0.82 | ALDH1A1 (0.46) | ITGB3ITGAVITGA2BITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |