Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905098 | 0.92 | ITGB1 (0.50) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL7908666 | 0.91 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL7906197 | 0.90 | CCR2 (0.44) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL7896620 | 0.87 | DPP4 (0.35) | — | |
| SCHEMBL7896693 | 0.86 | ITGB1 (0.47) | ITGA4ITGB1ITGA2ITGB7ITGB3 | |
| SCHEMBL7908862 | 0.84 | ALDH1A1 (0.46) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL6931396 | 0.84 | SLC7A5 (0.34) | ITGA4ITGB1ITGB7ITGB3ITGA2B | |
| SCHEMBL7906194 | 0.82 | ITGA4 (0.41) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL7896749 | 0.82 | ITGA4 (0.52) | ITGA4ITGB1ITGA2ITGB7ITGB3 | |
| SCHEMBL7905211 | 0.82 | ITGB1 (0.43) | ITGA4ITGB1ITGA2ITGB7ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | claimed |
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |