Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709540 | 0.92 | NOS3 (0.43) | ITGB1ITGA4ACKR3AGTR2RECQL | |
| SCHEMBL7905098 | 0.88 | ITGB1 (0.50) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL7896707 | 0.83 | GAA (0.45) | ITGB1ITGA4TPH1WEE1ITGAV | |
| SCHEMBL6933976 | 0.83 | ITGA4 (0.46) | ITGB1ITGA4 | |
| SCHEMBL7906141 | 0.82 | CYP3A4 (0.39) | ITGA4TPH1SMN1; SMN2AGTR2 | |
| SCHEMBL7896702 | 0.82 | TPH1 (0.37) | ITGB1ITGA4TPH1WEE1AGTR2 | |
| SCHEMBL7905121 | 0.82 | ITGA4 (0.42) | ITGB1ITGA4ITGA2ITGB7ITGB3 | |
| SCHEMBL7896693 | 0.82 | ITGB1 (0.47) | ITGB1ITGA4TPH1ITGA2ITGB7 | |
| SCHEMBL7908666 | 0.81 | ITGB1 (0.52) | ITGB1ITGA4 | |
| SCHEMBL7906163 | 0.81 | L3MBTL1 (0.36) | ITGB1SMN1; SMN2ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |