Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896693 | 0.90 | ITGB1 (0.47) | TPH1ITGB1ITGA4ITGB3ITGAV | |
| SCHEMBL7905098 | 0.89 | ITGB1 (0.50) | ITGB1ITGA4 | |
| SCHEMBL8200203 | 0.86 | TPH1 (0.38) | TPH1 | |
| SCHEMBL7905121 | 0.84 | ITGA4 (0.42) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL7908666 | 0.84 | ITGB1 (0.52) | ITGB1ITGA4 | |
| SCHEMBL7896749 | 0.84 | ITGA4 (0.52) | TPH1ITGB1ITGA4ITGB3ITGAV | |
| SCHEMBL7906194 | 0.82 | ITGA4 (0.41) | ALDH1A1LMNAGAAMAPTITGB1 | |
| SCHEMBL6934867 | 0.82 | LTA4H (0.39) | TPH1 | |
| SCHEMBL7906163 | 0.82 | L3MBTL1 (0.36) | ALDH1A1LMNAMAPTSMN1; SMN2ITGB1 | |
| SCHEMBL7906197 | 0.82 | CCR2 (0.44) | TPH1ITGB1ITGA4ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |