Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.40 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903943 | 0.87 | QPCT (0.42) | QPCTQPCTLHRH3ATMSPIN1 | |
| SCHEMBL7905966 | 0.84 | CYP2D6 (0.49) | QPCTQPCTLHRH3ATMCYP2D6 | |
| SCHEMBL7904007 | 0.81 | USP2 (0.40) | HRH3AXLLMNAKDM4ETDP1 | |
| SCHEMBL7905773 | 0.75 | BACE1 (0.39) | HRH3CYP2D6CYP3A4AXLLMNA | |
| SCHEMBL7896424 | 0.74 | ALDH1A1 (0.42) | HRH3LMNAKDM4E | |
| SCHEMBL7908470 | 0.73 | HRH3 (0.44) | HRH3LMNAKDM4E | |
| SCHEMBL7904684 | 0.72 | RAB9A (0.39) | HRH3ADORA2ATSHRLMNAKDM4E | |
| SCHEMBL7908545 | 0.72 | PRKDC (0.39) | CYP2D6CYP3A4AXLLMNAKIT | |
| SCHEMBL7904632 | 0.70 | HRH3 (0.41) | HRH3CYP2D6ADORA2ATSHRLMNA | |
| SCHEMBL7902709 | 0.70 | SMN1; SMN2 (0.44) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |