Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906197 | 0.87 | CCR2 (0.44) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL7908666 | 0.85 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL7896693 | 0.84 | ITGB1 (0.47) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL7906163 | 0.83 | L3MBTL1 (0.36) | ITGB1ITGB3ITGAVITGA2BALDH1A1 | |
| SCHEMBL7905098 | 0.83 | ITGB1 (0.50) | ITGA4ITGB1 | |
| SCHEMBL7908862 | 0.82 | ALDH1A1 (0.46) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL7905121 | 0.82 | ITGA4 (0.42) | ITGA4ITGB1ITGB3ITGAVITGA2B | |
| SCHEMBL6934867 | 0.82 | LTA4H (0.39) | MMP2 | |
| SCHEMBL7906161 | 0.81 | GRB2 (0.47) | — | |
| Phenylalanine SCHEMBL7906184 | 0.80 | SLC7A5 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |