Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759603 | 0.77 | CTSS (0.51) | LMNACTSSCTSLALDH1A1NPSR1 | |
| SCHEMBL2117209 | 0.77 | LMNA (0.62) | LMNAALDH1A1NPSR1CHRM2CHRM4 | |
| SCHEMBL9547536 | 0.76 | LMNA (0.73) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL6927610 | 0.76 | ALDH1A1 (0.52) | LMNACTSSCTSLALDH1A1CTSB | |
| SCHEMBL10340129 | 0.74 | POLB (0.65) | LMNACTSSCTSLALDH1A1CHRM2 | |
| SCHEMBL9550362 | 0.74 | CES2 (0.42) | LMNACTSSCTSLALDH1A1NPSR1 | |
| SCHEMBL16179158 | 0.73 | ALDH1A1 (0.57) | LMNACTSSCTSLALDH1A1NPSR1 | |
| SCHEMBL2526727 | 0.73 | LMNA (0.57) | LMNAALDH1A1MEN1KMT2ATSPO | |
| SCHEMBL9547626 | 0.72 | LMNA (0.92) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL1059560 | 0.72 | LMNA (0.56) | LMNAALDH1A1NPSR1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211270-B1 | HEAT AND LIGHT STABILIZERS FOR POLYMERS | WITCO VINYL ADDITIVES GMBH (DE) | 2001-04-03 | — | — | US | disclosed |