Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868717 | 0.76 | PDCD1 (0.41) | CTSSCTSLALDH1A1HPGDMAPT | |
| SCHEMBL2728050 | 0.76 | HSD11B1 (0.47) | CES2CES1CTSSCTSLALDH1A1 | |
| SCHEMBL25712472 | 0.74 | CTSS (0.46) | CES2CES1CTSSCTSLALDH1A1 | |
| SCHEMBL7919236 | 0.74 | LMNA (0.51) | CTSSCTSLALDH1A1POLBLMNA | |
| SCHEMBL10884719 | 0.73 | CTSS (0.44) | CES2CES1CTSSCTSLALDH1A1 | |
| SCHEMBL20494333 | 0.73 | CES1 (0.46) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL9725154 | 0.73 | CES2 (0.50) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL28250962 | 0.72 | POLB (0.43) | CES2CES1CTSSCTSLALDH1A1 | |
| SCHEMBL11691951 | 0.71 | CES2 (0.48) | CES2CES1ALDH1A1HPGDHSD11B1 | |
| SCHEMBL8166168 | 0.71 | HPGD (0.50) | CES2CES1ALDH1A1HPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |