Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 13/20 | 0.60 |
| ▸ | ACHE | P22303 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920783 | 0.77 | KEAP1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL561596 | 0.76 | KEAP1 (0.47) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2241139 | 0.75 | TDP1 (0.51) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2238587 | 0.75 | ALOX5 (0.49) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL562070 | 0.75 | KDM4E (0.49) | NPC1RAB9AKMT2A | |
| Potassium Ion SCHEMBL561597 | 0.73 | HDAC3 (0.46) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL12289378 | 0.73 | RAB9A (0.74) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10351423 | 0.73 | TSHR (0.48) | NPC1 | |
| SCHEMBL10777388 | 0.73 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2 | |
| SCHEMBL12040742 | 0.72 | KMT2A (0.62) | BCHEACHENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240463-B1 | SUBSTITUTED AMINOOXYPROPION AMIDES | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | claimed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | claimed |
| US-5057563-A | Oxidation, heat, radiation stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0240463-B1 | SUBSTITUTED AMINOOXYPROPION AMIDES | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | disclosed |
| US-4929657-A | STABILIZERS AGAINST OXIDATION, RADIATION FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |