Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820745 | 0.81 | CRBN (0.53) | CRBNMMP2MMP9MMP14TRPA1 | |
| SCHEMBL4595077 | 0.77 | CRBN (0.55) | CRBNMMP2MMP9MMP14TRPA1 | |
| SCHEMBL7430258 | 0.74 | MMP2 (0.52) | MMP2MMP9MMP14MMP1MMP8 | |
| SCHEMBL4613041 | 0.73 | CTSK (0.77) | CTSK | |
| SCHEMBL4613043 | 0.73 | CTSK (0.77) | CTSK | |
| SCHEMBL7916925 | 0.72 | MMP2 (0.50) | MMP2MMP9MMP14MMP1MMP8 | |
| SCHEMBL13448628 | 0.70 | PTGS2 (0.39) | CRBNKMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL8643198 | 0.70 | AOC2 (0.55) | CRBNMMP2MMP9MMP14CYP3A4 | |
| SCHEMBL30882890 | 0.69 | PTGS1 (0.56) | TRPA1 | |
| SCHEMBL27659898 | 0.69 | CRBN (0.51) | CRBNMMP2MMP9MMP14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |