SCHEMBL7929318

SCHEMBL7929318

O=S(=O)(c1ccc(F)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.57
MMP2 P08253 2/20 0.57
MMP9 P14780 2/20 0.57
MMP13 P45452 2/20 0.57
MMP3 P08254 1/20 0.57
MMP12 P39900 1/20 0.57
MMP14 P50281 1/20 0.57
HTR6 P50406 1/20 0.54
LMNA P02545 3/20 0.54
ALDH1A1 P00352 2/20 0.54
HTT P42858 2/20 0.54
MEN1 O00255 1/20 0.54
MITF O75030 1/20 0.54
MAPT P10636 1/20 0.54
CASP6 P55212 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA12 O43570 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7938152 0.96 HTR6 (0.61) MMP1MMP2MMP9MMP13MMP3
SCHEMBL5518610 0.91 PTGS2 (0.50) MMP1MMP2MMP9MMP13MMP3
SCHEMBL2006278 0.91 PTGS2 (0.50) MMP1MMP2MMP9MMP13MMP3
SCHEMBL5527318 0.91 PTGS2 (0.50) MMP1MMP2MMP9MMP13MMP3
SCHEMBL778229 0.89 HTR6 (0.70) MMP1MMP2MMP9MMP13MMP3
SCHEMBL11980110 0.89 HTR6 (0.70) MMP1MMP2MMP9MMP13MMP3
SCHEMBL7937274 0.89 HTR6 (0.70) MMP1MMP2MMP9MMP13MMP3
SCHEMBL18194389 0.89 HTR6 (0.68) MMP1MMP2MMP9MMP13MMP3
SCHEMBL9001233 0.89 HTR6 (0.68) MMP1MMP2MMP9MMP13MMP3
SCHEMBL18059988 0.87 LMNA (0.51) MMP1MMP2MMP9MMP13MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7736539-B2 Ion-conducting polymers and membranes comprising them JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-06-15 US disclosed
US-7736539-B2 Ion-conducting polymers and membranes comprising them JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-06-15 US disclosed
EP-1704175-B1 ION-CONDUCTING POLYMERS AND MEMBRANES COMPRISING THEM JOHNSON MATTHEY PLC (GB) 2008-10-15 EP disclosed
US-20070196734-A1 Ion-Conducting Polymers And Membranes Comprising Them Johnson Matthey Hydrogen Technologies Limited (GB) 2007-08-23 US disclosed
US-20070196734-A1 Ion-Conducting Polymers And Membranes Comprising Them Johnson Matthey Hydrogen Technologies Limited (GB) 2007-08-23 US disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed