Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929318 | 0.96 | MMP1 (0.57) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL778229 | 0.93 | HTR6 (0.70) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL7937274 | 0.93 | HTR6 (0.70) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL11980110 | 0.93 | HTR6 (0.70) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL2006278 | 0.91 | PTGS2 (0.50) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL5527318 | 0.91 | PTGS2 (0.50) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL5518610 | 0.91 | PTGS2 (0.50) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL197508 | 0.89 | HTR6 (0.78) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL4076387 | 0.86 | CA2 (0.50) | HTR6MMP1MMP2MMP3MMP9 | |
| SCHEMBL3026340 | 0.86 | HTR6 (0.74) | HTR6MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |