SCHEMBL7932619

SCHEMBL7932619

O=C1CC(CBr)C(=O)N1c1ccccc1Cc1ccccc1N1C(=O)CC(CBr)C1=O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
GAA P10253 2/20 0.45
GFER P55789 1/20 0.45
TSHR P16473 2/20 0.44
MT-CO2 P00403 1/20 0.41
ALOX5 P09917 1/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
ALDH1A1 P00352 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.38
MGLL Q99685 1/20 0.38
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10569729 0.81 KMT2A (0.46) GAATSHRMT-CO2ALOX5KMT2A
SCHEMBL10572666 0.78 ALDH1A1 (0.55) TSHRMT-CO2ALOX5KMT2AMEN1
SCHEMBL10569258 0.72 MGLL (0.46) LMNAGAAGFERTSHRMT-CO2
SCHEMBL10571049 0.71 ADAM17 (0.39) MT-CO2ALOX5KMT2AMEN1ALDH1A1
SCHEMBL10565374 0.70 ALDH1A1 (0.55) GAAMT-CO2ALOX5KMT2AMEN1
SCHEMBL10569171 0.70 HTR1A (0.40) KMT2AMEN1ALDH1A1L3MBTL1MAPT
SCHEMBL10574683 0.70 ADRA1B (0.43) ALDH1A1MAPT
SCHEMBL10569834 0.69 POLB (0.60) LMNAGAATSHRMT-CO2ALOX5
SCHEMBL10571192 0.68 MT-CO2 (0.47) TSHRMT-CO2ALOX5KMT2AMEN1
SCHEMBL10571688 0.68 ALDH1A1 (0.54) GAATSHRMT-CO2ALOX5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800551-B1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL NV (NL) 2001-06-13 EP disclosed
US-5844049-A Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds AKZO NOBEL NV (NL) 1998-12-01 US disclosed
EP-0800551-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS Akzo Nobel N.V. (NL) 1997-10-15 EP disclosed
WO-1996020246-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL N.V. (NL) 1996-07-04 WO disclosed