Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934373 | 0.89 | ALOX5 (0.41) | RECQLALDH1A1LMNAEDNRBEDNRA | |
| SCHEMBL7936594 | 0.75 | KMT2A (0.45) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7928120 | 0.73 | EDNRB (0.44) | MAPTKDM4EMEN1RECQLKMT2A | |
| SCHEMBL7934306 | 0.68 | EDNRB (0.46) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5521119 | 0.67 | MAOB (0.45) | MAPTKDM4EMEN1RECQLKMT2A | |
| Bicarbonate SCHEMBL11298239 | 0.64 | KDM4E (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5160744 | 0.62 | ALDH1A1 (0.56) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7937196 | 0.62 | EDNRB (0.49) | EDNRBEDNRA | |
| SCHEMBL1069539 | 0.61 | EDNRB (0.55) | EDNRBEDNRA | |
| SCHEMBL9082340 | 0.60 | ADORA3 (0.40) | MAPTKDM4EALDH1A1LMNAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235903-B1 | Method for preparing sulfanyl-type endothelin receptor antagonists | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |