SCHEMBL7937550

SCHEMBL7937550

CC=CC(=O)CCCC(C)(O[SiH3])c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
ALOX5 P09917 2/20 0.34
IAPP P10997 2/20 0.33
LMNA P02545 5/20 0.32
MAPT P10636 4/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR1 P21453 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KMT2A Q03164 2/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3309534 0.82 AKR1B10 (0.39) ALDH1A1ALOX5LMNAKDM4EKMT2A
SCHEMBL3481672 0.73 MAPK1 (0.38) ALDH1A1KCNN4CNR2
SCHEMBL5180283 0.73 MAPK1 (0.38) ALDH1A1KMT2AKCNN4MEN1CNR2
SCHEMBL7161569 0.72 THRB (0.47) ALDH1A1HIF1AALOX5KDM4ETP53
SCHEMBL7872447 0.69 TDP1 (0.44) CYP2C19HIF1ACYP3A4PPARA
SCHEMBL3481487 0.69 MAPK1 (0.40) ALDH1A1CYP2C19HIF1ALMNAKDM4E
SCHEMBL10459316 0.68 CNR2 (0.34) CYP2C19HIF1ALMNAMAPTKDM4E
SCHEMBL3476767 0.68 KIF11 (0.31) CYP2C19HIF1AKCNH2
SCHEMBL9449505 0.67 HDAC3 (0.45) ALDH1A1CYP2C19HIF1AMAPTNPSR1
SCHEMBL9449951 0.67 HDAC3 (0.45) ALDH1A1CYP2C19HIF1AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207235-B1 POLYMER CONTAINING ACID ANHYDRIDE GROUP, BLOCKED HYDROXYL GROUP AND EPOXY GROUP, HEAT CURING CATALYST COMPRISING COMPLEX OF ORGANOMETALLIC COMPOUND AND ELECTRON-DONATING COMPOUND OR ONIUM SALT, ULTRAVIOLET ABSORBER, HINDERED AMINE STABILIZER MAZDA MOTOR CORPORATION (JP) 2001-03-27 US disclosed