Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.83 |
| ▸ | LMNA | P02545 | 4/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.65 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835108 | 0.91 | HPGD (1.00) | HPGDLMNAL3MBTL1ALDH1A1HSD17B1 | |
| SCHEMBL1755726 | 0.91 | HPGD (1.00) | HPGDLMNAL3MBTL1ALDH1A1HSD17B1 | |
| 4-Hydroxyacetophenone SCHEMBL8934912 | 0.86 | HSD17B1 (0.85) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL40866 | 0.86 | HSD17B1 (0.85) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL9480590 | 0.84 | HSD17B1 (0.81) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL27639603 | 0.84 | HSD17B1 (0.81) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL28050008 | 0.84 | HSD17B1 (0.81) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL8744798 | 0.84 | HSD17B1 (0.81) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL31385561 | 0.84 | HSD17B1 (0.81) | HPGDLMNAL3MBTL1HSD17B1MAPT | |
| 4-Hydroxyacetophenone SCHEMBL28895846 | 0.84 | HSD17B1 (0.81) | HPGDLMNAL3MBTL1HSD17B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-08-30 | — | — | US | disclosed |
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | U.S. DEPARTMENT OF ENERGY | 2018-12-27 | — | — | US | disclosed |
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
| WO-2007096647-A2 | DIARYL COMPOUNDS AS NON-STEROIDAL INHIBITORS OF 17-BETA HYDROXYSTEROID DEHYDROGENASE AND/OR STEROID SULPHATASE FOR THE TREATMENT OF OESTROGEN-RELATED DISEASES SUCH AS HORMONE DEPENDENT BREAST CANCER | STERIX LIMITED (GB) | 2007-08-30 | — | — | WO | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| EP-0324472-B1 | KETENEDITHIOACETAL DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME AS WELL AS A COMPOSITION CONTAINING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5098928-A | Antilipemic agents and treatment of arteriosclerosis | NIHON NOHYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0324472-A2 | Ketenedithioacetal derivatives and processes for producing the same as well as a composition containing the same | NIHON NOHYAKU CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | TST, CBS, CRY2 | HPGD 1394/4885LMNA 4215/4885L3MBTL1 1004/4885 |
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | HPGD 61/4885LMNA 1964/4885L3MBTL1 4333/4885 |
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | TST, CBS, CRY2 | HPGD 1394/4885LMNA 4215/4885L3MBTL1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.